BDBM50132292 5-Ethyl-1-((2R,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione::5-ethyl-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione::5-ethyl-2'-deoxyuridine::CHEMBL318153::Edoxudine::cid_1814::cid_66377

SMILES CCc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O

InChI Key InChIKey=XACKNLSZYYIACO-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50132292   

TargetThymidine kinase(CeHV-1)
Glsynthesis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132292BDBM50132292(CHEMBL318153 | 5-Ethyl-1-((2R,5R)-4-hydroxy-5-hydr...)
Affinity DataIC50: 150nMAssay Description:Inhibition of Herpes B virus recombinant thymidine kinase-mediated [3H]TdR phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Ghent University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132292BDBM50132292(CHEMBL318153 | 5-Ethyl-1-((2R,5R)-4-hydroxy-5-hydr...)
Affinity DataKi:  1.14E+6nMAssay Description:Inhibitory activity against thymidine monophosphate kinase (TMPK) in Mycobacterium tuberculosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed