BDBM50143424 2-(3-hydroxy-6-oxo-6H-xanthen-9-yl)benzoic acid::2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)-benzoic acid::2-(6-oxido-3-oxo-3H-xanthen-9-yl)benzoate::3',6'-dihydroxyspiro[1,3-dihydroisobenzofuran-1,9'-(9'H-xanthene)]-3-one::CHEMBL177756::FLUORESCEIN::Fluorescite::Funduscein-25::cid_3383

SMILES OC(=O)c1ccccc1-c1c2ccc(O)cc2oc2cc(=O)ccc12

InChI Key InChIKey=YKGGGCXBWXHKIZ-UHFFFAOYSA-N

Data  2 KI  5 IC50

PDB links: 11 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50143424   

TargetSolute carrier family 22 member 6(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50143424(2-(3-hydroxy-6-oxo-6H-xanthen-9-yl)benzoic acid | ...)
Affinity DataKi:  2.95E+3nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 20(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50143424(2-(3-hydroxy-6-oxo-6H-xanthen-9-yl)benzoic acid | ...)
Affinity DataKi:  1.00E+5nMAssay Description:Inhibition of mouse Oat6-mediated [3H]ES uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50143424(2-(3-hydroxy-6-oxo-6H-xanthen-9-yl)benzoic acid | ...)
Affinity DataIC50:  6.00E+5nMAssay Description:Inhibition of human PTPase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRmtA(Emericella nidulans)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50143424(2-(3-hydroxy-6-oxo-6H-xanthen-9-yl)benzoic acid | ...)
Affinity DataIC50:  1.23E+5nMAssay Description:Inhibition of Aspergillus nidulans recombinant GST-RmtA expressed in BL21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase 1(Saccharomyces cerevisiae)
Inha University

Curated by ChEMBL
LigandPNGBDBM50143424(2-(3-hydroxy-6-oxo-6H-xanthen-9-yl)benzoic acid | ...)
Affinity DataIC50:  8.50E+5nMAssay Description:Inhibitory activity against Saccharomyces cerevisiae Tyrosine phosphatase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMothers against decapentaplegic homolog 3(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM50143424(2-(3-hydroxy-6-oxo-6H-xanthen-9-yl)benzoic acid | ...)
Affinity DataIC50:  4.89E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: F.M. Hoffmann, University ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50143424(2-(3-hydroxy-6-oxo-6H-xanthen-9-yl)benzoic acid | ...)
Affinity DataIC50:  7.50E+4nMAssay Description:Inhibition of human recombinant GST-PRMT1 expressed in BL21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed