BDBM50080153 (1-Aminomethyl-cyclohexyl)-acetic acid::2-(1-(aminomethyl)cyclohexyl)acetic acid::CHEMBL940::CI-945::GABAPENTIN::GOE-3450::Neurontin::[1-(AMINOMETHYL)CYCLOHEXYL]ACETIC ACID
SMILES NCC1(CC(O)=O)CCCCC1
InChI Key InChIKey=UGJMXCAKCUNAIE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50080153
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Mus musculus)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 120nMAssay Description:Displacement of [3H]L-leucine from alpha2delta containing calcium channel in murine brainMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Displacement of [3H]gabapentin from alpha-2delta calcium channel in pig brain membraneMore data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Rattus norvegicus)
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of potassium-evoked [3H]norepinephrine release from rat neocortexMore data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Binding affinity towards alpha2-delta subunit of a voltage gated calcium channel using [3H]-gabapentin in human brain membrane (A710 membrane)More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 minsMore data for this Ligand-Target Pair