BDBM50369240 GANAXOLONE

SMILES CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@](C)(O)CC[C@]4(C)[C@H]3CC[C@]12C

InChI Key InChIKey=PGTVWKLGGCQMBR-FLBATMFCSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50369240   

TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Cocensys

Curated by ChEMBL
LigandPNGBDBM50369240(GANAXOLONE)
Affinity DataEC50:  260nMAssay Description:Potentiation of GABA-activated currents in Xenopus oocytes expressing cloned human alpha-1-beta-2-gamma-2L subunits of GABA-A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50369240(GANAXOLONE)
Affinity DataEC50:  100nMAssay Description:Positive allosteric modulation of human GABAA alpha2beta1gamma2 receptor expressed in Xenopus laevis oocytes by two-microelectrode voltage-clamp assa...More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50369240(GANAXOLONE)
Affinity DataEC50:  200nMAssay Description:Positive allosteric modulation of human GABAA alpha1beta2gamma2 receptor expressed in Xenopus laevis oocytes by two-microelectrode voltage-clamp assa...More data for this Ligand-Target Pair
In DepthDetails PubMed