BDBM50366778 47663::Aktob::Nebcin::Nebicin::Nebramycin::Nebramycin Factor 6::Obramycin::TOBRAMYCIN::Tobi::Tobradex::Tobradex ST

SMILES NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O

InChI Key InChIKey=NLVFBUXFDBBNBW-PBSUHMDJSA-N

Data  4 IC50  1 Kd

PDB links: 13 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50366778   

TargetProtein Rev(Human immunodeficiency virus 1)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50366778(47663 | Aktob | Nebcin | Nebicin | Nebramycin | Ne...)
Affinity DataKd:  4.11E+3nMAssay Description:Tetsed for the ability to bind the HIV-1 RRE-RNA construct by fluorescence anisotropyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50366778(47663 | Aktob | Nebcin | Nebicin | Nebramycin | Ne...)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50366778(47663 | Aktob | Nebcin | Nebicin | Nebramycin | Ne...)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50366778(47663 | Aktob | Nebcin | Nebicin | Nebramycin | Ne...)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50366778(47663 | Aktob | Nebcin | Nebicin | Nebramycin | Ne...)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed