BDBM41951 MLS000696629::N'-(4,6-dimethyl-1,3-benzothiazol-2-yl)-4-(3,5-dimethylpiperidin-1-yl)sulfonyl-benzohydrazide::N'-(4,6-dimethyl-1,3-benzothiazol-2-yl)-4-(3,5-dimethylpiperidin-1-yl)sulfonylbenzohydrazide::N'-(4,6-dimethyl-1,3-benzothiazol-2-yl)-4-(3,5-dimethylpiperidino)sulfonyl-benzohydrazide::N'-(4,6-dimethyl-1,3-benzothiazol-2-yl)-4-[(3,5-dimethyl-1-piperidinyl)sulfonyl]benzohydrazide::SMR000235772::cid_12006126

SMILES N1(C=NC=C1)C1=CC=C(C=N1)C#CC=1C=NC(=NC1)N1C[C@@H](N(CC1)C1=NC=CC=N1)CO

InChI Key InChIKey=IQZVXPPZNRDUKJ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 41951   

TargetAlpha-synuclein(Human)
Merck Sharp & Dohme

WIPO
LigandChemical structure of BindingDB Monomer ID 41951BDBM41951((R)-(4-(5-((6-(1H-imidazol-1-yl)pyridin-3-yl)ethyn...)
Affinity DataKi:  49nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
WIPO WO2024186584

TargetAmyloid-beta precursor protein(Human)
Merck Sharp & Dohme

WIPO
LigandChemical structure of BindingDB Monomer ID 41951BDBM41951((R)-(4-(5-((6-(1H-imidazol-1-yl)pyridin-3-yl)ethyn...)
Affinity DataKi:  1.20E+4nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
WIPO WO2024186584