BDBM458793 6-(Ethyl(tetrahydro-2H-pyran-4-yl)amino)-N-((4-methoxy-6-methyl-2-oxo-1,2-dihydro pyridin-3-yl)methyl)-5-methyl-2-(piperidin-1-ylmethyl)benzofuran-4-carboxamide::US10759787, Example 4::US11059811, Example 4
SMILES CCN(C1CCOCC1)c1cc2oc(CN3CCCCC3)cc2c(C(=O)NCc2c(OC)cc(C)[nH]c2=O)c1C
InChI Key InChIKey=SKNQQJYNBYGLET-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 458793
TargetHistone-lysine N-methyltransferase EZH2 [A677G](Homo sapiens (Human))
Jiangsu Hengrui Medicine
US Patent
Jiangsu Hengrui Medicine
US Patent
Affinity DataIC50: 14nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair