BDBM246861 3-[1-(6- chloropyridin-2- yl)pyrrolidin-3-yl]-3- [4-(7H-pyrrolo[2,3- d]pyrimidin-4-yl)- 1H-pyrazol-1- yl]propanenitrile::US10005788, 2 (2nd peak, cis-)::US10053465, 3::US10065963, Compound 3::US10125150, Example 3::US10336759, # 3::US10479803, Example 3::US10519163, Example 3::US10675284, Example 3::US11084822, Example 3::US11130767, # 3::US11136326, Example 3::US11304949, Compound 6::US11324749, Comp. No. 6::US11406640, Comp. No. 6::US11596632, Comp. No. 6::US20240058343, Compound 6::US9732097, Example 3
SMILES Clc1cccc(n1)N1CCC(C1)C(CC#N)n1cc(cn1)-c1ncnc2[nH]ccc12
InChI Key
Data 36 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 246861
Affinity DataIC50: <10nMAssay Description:JAK1 pathway inhibitors that can be used for the treatment of cytokine-related diseases or disorders are tested for inhibitory activity of JAK target...More data for this Ligand-Target Pair