BDBM474221 8-(2,6-dimethylpyridin-4-yl)-7-(4-fluoropheny1)- 2-[(3-fluoropyridin-2-yl)methyl]-[l,2,4]triazolo [1,5-c]pyrimidin-5-amine::US10858365, Compound 1::US11629147, Cmpd. 1

SMILES Cn1cc(ccc1=O)-c1c(nc(N)n2nc(Cc3ncccc3F)nc12)-c1ccc(F)cc1

InChI Key InChIKey=CUMVKGYWZJOYNO-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 474221   

TargetAdenosine receptor A3(Human)
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandPNGBDBM474221(8-(2,6-dimethylpyridin-4-yl)-7-(4-fluoropheny1)- 2...)
Affinity DataIC50:  2.87E+3nMAssay Description:Binding affinity and specificities of the compounds against different subtype of human adenosine receptors (hA1, hA2A, hA2B and hA3) were characteriz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetAdenosine receptor A2a(Human)
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandPNGBDBM474221(8-(2,6-dimethylpyridin-4-yl)-7-(4-fluoropheny1)- 2...)
Affinity DataIC50:  2.30nMAssay Description:Binding affinity and specificities of the compounds against different subtype of human adenosine receptors (hA1, hA2A, hA2B and hA3) were characteriz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetAdenosine receptor A1(Human)
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandPNGBDBM474221(8-(2,6-dimethylpyridin-4-yl)-7-(4-fluoropheny1)- 2...)
Affinity DataIC50:  1.10nMAssay Description:Binding affinity and specificities of the compounds against different subtype of human adenosine receptors (hA1, hA2A, hA2B and hA3) were characteriz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetAdenosine receptor A2b(Human)
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandPNGBDBM474221(8-(2,6-dimethylpyridin-4-yl)-7-(4-fluoropheny1)- 2...)
Affinity DataIC50:  2.30nMAssay Description:Binding affinity and specificities of the compounds against different subtype of human adenosine receptors (hA1, hA2A, hA2B and hA3) were characteriz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent