BDBM473689 1-Isopropyl-3-(1H-pyrrolo[2,3-b]pyridin-2- yl)-1H-pyrazolo[4,3-c]pyridin-4-amine::US10844067, Example 32::US11661423, Example 32
SMILES CC(C)n1nc(-c2cc3cccnc3[nH]2)c2c(N)nccc12
InChI Key InChIKey=KSCKIOGOWXGQCD-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 473689
TargetProto-oncogene tyrosine-protein kinase receptor Ret [V804M](Homo sapiens (Human))
Cancer Research Technology
US Patent
Cancer Research Technology
US Patent
Affinity DataIC50: 621nMAssay Description:Kinase activity was detected using CisBio HTRF kinEASE kit based on time-resolved fluorescence transfer (FRET). The assay was performed in 384-well w...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Cancer Research Technology
US Patent
Cancer Research Technology
US Patent
Affinity DataIC50: 3.5nMAssay Description:Kinase activity was detected using CisBio HTRF kinEASE kit based on time-resolved fluorescence transfer (FRET). The assay was performed in 384-well w...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cancer Research Technology
US Patent
Cancer Research Technology
US Patent
Affinity DataIC50: 210nMAssay Description:Kinase activity was detected using CisBio HTRF kinEASE kit based on time-resolved fluorescence transfer (FRET). The assay was performed in 384-well w...More data for this Ligand-Target Pair