BDBM293512 US10106527, Compound 134::US10544128, Compound 134::US11548872, Compound 134::US20230286945, Compound 134::US9951048, Compound 134

SMILES CN1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(-c3cnn(C)c3)c(F)cc2cn1

InChI Key InChIKey=XYOONDKQDDKZSA-UHFFFAOYSA-N

Data  10 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 293512   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Biosplice Therapeutics

US Patent
LigandPNGBDBM293512(US10106527, Compound 134 | US10544128, Compound 13...)
Affinity DataEC50:  1.60nMAssay Description:The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies a Divis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Biosplice Therapeutics

US Patent
LigandPNGBDBM293512(US10106527, Compound 134 | US10544128, Compound 13...)
Affinity DataEC50: >1.00E+4nMAssay Description:The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies a Di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent