BDBM50196630 CHEMBL3942452::US10167270, Compound 8d

SMILES C(CNc1nc(nc2ccccc12)-c1cccnc1)Cc1ccccc1

InChI Key InChIKey=KNPAHIAFSKZRIB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50196630   

TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University

US Patent
LigandPNGBDBM50196630(CHEMBL3942452 | US10167270, Compound 8d)
Affinity DataIC50:  1.53E+3nMAssay Description:The enzyme in GCase enzyme activity buffer (25 μL/well) was added to a 384-well black plate. The fluorescent probe 3 (25 nL/well, 50 nM final co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University

US Patent
LigandPNGBDBM50196630(CHEMBL3942452 | US10167270, Compound 8d)
Affinity DataIC50:  1.78E+3nMAssay Description:The enzyme in GCase enzyme activity buffer (25 μL/well) was added to a 384-well black plate. The fluorescent probe 3 (25 nL/well, 50 nM final co...More data for this Ligand-Target Pair
In DepthDetails US Patent