BDBM88664 US10189794, Compound I-27::US10618902, Compound I-27::US10774052, Compound I-27::US9695132, I-27

SMILES COc1cc(OC)cc(c1)N1Cc2cnc(Nc3cc(ccc3NC(=O)C=C)-c3cnn(C)c3)nc2N(C)C1=O

InChI Key InChIKey=AJASVIXFAYLXIB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 88664   

TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Celgene Car

US Patent
LigandPNGBDBM88664(US10189794, Compound I-27 | US10618902, Compound I...)
Affinity DataIC50: <100nMAssay Description:A 10× stock solution of FGFR4-WT (PR4380C), (from Invitrogen, Carlsbad, Calif.) corresponding to method a in Table 7, was prepared as described below...More data for this Ligand-Target Pair
In DepthDetails US Patent