BDBM2683 2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-3-yl)maleimide::3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-(1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione::BIM-1::CHEMBL7463::GF 109203X::JMC526193 Compound 2
SMILES CN(C)CCCn1cc(C2=C(C(=O)NC2=O)c2c[nH]c3ccccc23)c2ccccc12
InChI Key InChIKey=QMGUOJYZJKLOLH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 2683
Affinity DataKd: 10nMAssay Description:Binding affinity to non phosphorylated PIM1More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibitory activity against PIM1More data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 1 hit for monomerid = 2683
ITC DataΔG°: -10.4kcal/mole −TΔS°: 3.84kcal/mole ΔH°: -14.3kcal/mole logk: 9.86E+7
pH: 7.5 T: 10.00°C
pH: 7.5 T: 10.00°C