BDBM110622 US8614234, 90::US9725433, 90
SMILES Cc1cccc(NC(=O)Nc2ccc(Oc3ccnc(c3)-c3cc(c[nH]3)C(=O)N3CCC[C@@H](O)C3)cc2)c1
InChI Key InChIKey=AGFATOYGCIURQX-HSZRJFAPSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 110622
Affinity DataIC50: 6nMAssay Description:The cytoplasmic domain of the human VEGF receptor (VEGFR-2) was expressed as a Histidine-tagged fusion protein following infection of insect cells us...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of VEGF induced increases in intracellular calcium l...More data for this Ligand-Target Pair