BDBM127641 US10251889, Example 14::US10758542, Example 14::US8791123, 14::US9782415, Example 14::US9796724, Example 14

SMILES Fc1ccc(F)c(c1)[C@H]1CCCN1c1ccn2ncc(C(=O)NC3CCC3)c2n1

InChI Key InChIKey=PKQSRPZFIGJTJF-GOSISDBHSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 127641   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharm

US Patent
LigandPNGBDBM127641(US10251889, Example 14 | US10758542, Example 14 | ...)
Affinity DataIC50:  470nMAssay Description:An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Array Biopharm

US Patent
LigandPNGBDBM127641(US10251889, Example 14 | US10758542, Example 14 | ...)
Affinity DataIC50:  0.550nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Jak2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In DepthDetails US Patent