BDBM50355500 CHEMBL1908394::US9695172, GSK461364

SMILES C[C@@H](Oc1cc(sc1C(N)=O)-n1cnc2ccc(CN3CCN(C)CC3)cc12)c1ccccc1C(F)(F)F

InChI Key InChIKey=ZHJGWYRLJUCMRT-QGZVFWFLSA-N

Data  3 KI  4 IC50  444 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50355500   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50355500(CHEMBL1908394 | US9695172, GSK461364)
Affinity DataIC50: >5.00E+4nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150 mM ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBromodomain testis-specific protein(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50355500(CHEMBL1908394 | US9695172, GSK461364)
Affinity DataIC50: >5.00E+4nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150 mM ...More data for this Ligand-Target Pair
In DepthDetails US Patent