BDBM50357312 IBRUTINIB::PCI-32765::US10124003, Ref. Ex. Compound 1::US10711006, Compound Ibrutinib::US10793575, Example ibrutinib::US10835536, Ref. Ex. Comp 1::US10919899, Ibrutinib::US11078206, Example Ibrutinib::US11186578, Example Ibrutinib::US11339167, Example Ibrutinib::US11407754, Example Ibrutinib::US20230364079, Example Ibrutinib::US20240059694, Compound Ibrutinib::US20240139326, Compound Ibrutinib::US9108973, Ref 1::US9181263, 1::US9278100, 1
SMILES Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)[C@@H]1CCCN(C1)C(=O)C=C
InChI Key InChIKey=XYFPWWZEPKGCCK-GOSISDBHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50357312
TargetTyrosine-protein kinase Tec(Human)
National Institute of Biological Sciences, Beijing
Curated by ChEMBL
National Institute of Biological Sciences, Beijing
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human TEC using poly[Glu:Tyr] as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition by filter binding methodMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Human)
National Institute of Biological Sciences, Beijing
Curated by ChEMBL
National Institute of Biological Sciences, Beijing
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Human)
National Institute of Biological Sciences, Beijing
Curated by ChEMBL
National Institute of Biological Sciences, Beijing
Curated by ChEMBL
Affinity DataIC50: 0.110nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Tec(Human)
National Institute of Biological Sciences, Beijing
Curated by ChEMBL
National Institute of Biological Sciences, Beijing
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair