BDBM237925 US9394285, 6

SMILES OC(=O)c1c[nH]c2cc(F)c(-c3ccc(cc3)C3(O)CCC3)c(F)c12

InChI Key InChIKey=VPUNMIRZXILGLE-UHFFFAOYSA-N

Data  1 Kd  2 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 237925   

Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM237925(US9394285, 6)Copy SMILESCopy InChI

Affinity DataEC50:  35nMAssay Description:Allosteric activation of human AMPK alpha1/beta1/gamma1 by TR-FRET assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM237925(US9394285, 6)Copy SMILESCopy InChI

Affinity DataKd:  20nMAssay Description:Binding affinity to human BAP-tagged AMPK alpha1/beta1/gamma1 by SPR assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI