BDBM50131550 (3S)-3-{[(1S)-1-carbamoyl-2-{4-[difluoro(phosphono)methyl]phenyl}ethyl]carbamoyl}-3-(2-{4-[difluoro(phosphono)methyl]phenyl}acetamido)propanoic acid::(S)-4-((S)-1-amino-3-(4-(difluoro(phosphono)methyl)phenyl)-1-oxopropan-2-ylamino)-3-(2-(4-(difluoro(phosphono)methyl)phenyl)acetamido)-4-oxobutanoic acid::CHEMBL326115::N-{1-Carbamoyl-2-[4-(difluoro-phosphono-methyl)-phenyl]-ethyl}-3-{2-[4-(difluoro-phosphono-methyl)-phenyl]-acetylamino}-succinamic acid

SMILES NC(=O)[C@H](Cc1ccc(cc1)C(F)(F)P(O)(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)Cc1ccc(cc1)C(F)(F)P(O)(O)=O

InChI Key InChIKey=FKOYIUYWMSVYKN-IRXDYDNUSA-N

Data  14 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50131550   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50131550((3S)-3-{[(1S)-1-carbamoyl-2-{4-[difluoro(phosphono...)
Affinity DataKi:  2.40nMAssay Description:Inhibition of recombinant GST-tagged PTP1B (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrate measured after 2 to 3 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50131550((3S)-3-{[(1S)-1-carbamoyl-2-{4-[difluoro(phosphono...)
Affinity DataKi:  26nMAssay Description:Inhibition of recombinant human TCPTP catalytic domain (1 to 288 residues) expressed in Escherichia coli using pNPP as substrate measured after 2 to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed