BDBM50263285 CHEMBL4094904
SMILES COc1cccc(c1)-c1nc(Nc2cccc(c2)C(F)(F)F)c2cccnc2n1
InChI Key InChIKey=LJULRQVWBFAEFY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50263285
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn
Curated by ChEMBL
University of Bonn
Curated by ChEMBL
Affinity DataEC50: 85nMAssay Description:Agonist activity at human A1AR expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4 dye-based fluorescence assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn
Curated by ChEMBL
University of Bonn
Curated by ChEMBL
Affinity DataIC50: 539nMAssay Description:Inhibition of human ABCG2 expressed in MDCK2 cells assessed as increase in accumulation of Hoechst 33342 preincubated for 30 mins followed by Hoechst...More data for this Ligand-Target Pair