BDBM81818 CAS_1794::CHEMBL1909810::HMA::NSC_1794

SMILES NC(=N)NC(=O)c1nc(Cl)c(nc1N)N1CCCCCC1

InChI Key InChIKey=RQQJJXVETXFINY-UHFFFAOYSA-N

Data  34 KI  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 81818   

TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM81818(CAS_1794 | CHEMBL1909810 | HMA | NSC_1794)
Affinity DataKi:  1.36E+3nMAssay Description:Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Mus musculus (Mouse))
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM81818(CAS_1794 | CHEMBL1909810 | HMA | NSC_1794)
Affinity DataKi:  9.31E+3nMAssay Description:Inhibition of mouse uPA using Z-Gly-Gly-Arg-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM81818(CAS_1794 | CHEMBL1909810 | HMA | NSC_1794)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human plasma kallikrein using chromogenic L-pyroGlu-L-Pro-L-Arg-p-nitroaniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM81818(CAS_1794 | CHEMBL1909810 | HMA | NSC_1794)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of trypsin (unknown origin) using chromogenic H-D-Ile-L-Pro-L-Arg-p-nitoraniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM81818(CAS_1794 | CHEMBL1909810 | HMA | NSC_1794)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of activated protein C (unknown origin) using chromogenic L-pyroGlu-L-Pro-L-Arg-p-nitroaniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM81818(CAS_1794 | CHEMBL1909810 | HMA | NSC_1794)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of factor 10a (unknown origin) using chromogenic H-D-Ile-L-Pro-L-Arg-p-nitoraniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM81818(CAS_1794 | CHEMBL1909810 | HMA | NSC_1794)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of tPA (unknown origin) using chromogenic H-D-Ile-L-Pro-L-Arg-p-nitoraniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM81818(CAS_1794 | CHEMBL1909810 | HMA | NSC_1794)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human kidney uPA using chromogenic H-D-Ile-L-Pro-L-Arg-p-nitoraniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM81818(CAS_1794 | CHEMBL1909810 | HMA | NSC_1794)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of thrombin (unknown origin) using chromogenic H-D-Ile-L-Pro-L-Arg-p-nitoraniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM81818(CAS_1794 | CHEMBL1909810 | HMA | NSC_1794)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of plasmin (unknown origin) using chromogenic H-D-Ile-L-Pro-L-Arg-p-nitoraniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM81818(CAS_1794 | CHEMBL1909810 | HMA | NSC_1794)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of factor 11a (unknown origin) using chromogenic L-pyroGlu-L-Pro-L-Arg-p-nitroaniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed