BDBM50010704 CHEMBL216640::Dyn A(1-11)-NH2::Dynorphin A analogues::H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-NH2::HTyr-Gly-Gly-Phe-Leu-Arg-Arg-lle-Arg-Pro-LysNH2::Linear Dyn A-(1-11)NH2::Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-D-Lys-NH2::Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln-NH2

SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O

InChI Key InChIKey=OKJAOUBQLSWUNX-QFIUEGLPSA-N

Data  15 KI  12 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50010704   

TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50010704(CHEMBL216640 | Dyn A(1-11)-NH2 | Dynorphin A analo...)
Affinity DataIC50:  0.580nMAssay Description:Inhibition of binding [3H]U-69,539 at Opioid receptor kappa 1 of guinea pig brain membrane (GPB) homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50010704(CHEMBL216640 | Dyn A(1-11)-NH2 | Dynorphin A analo...)
Affinity DataIC50:  25.5nMAssay Description:Agonistic activity towards Opioid receptor delta 1 was determined by evaluating the inhibitory activity towards electrically stimulated mouse vas def...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50010704(CHEMBL216640 | Dyn A(1-11)-NH2 | Dynorphin A analo...)
Affinity DataIC50:  9.90nMAssay Description:Inhibition of binding [3H]-DAMGO at Opioid receptor mu 1 of guinea pig brain membrane (GPB) homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed