BDBM50318907 2-Ethoxy-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-benzoimidazole-4-carboxylic acid 1-cyclohexyloxycarbonyloxy-ethyl ester::2-Ethoxy-3-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-benzoimidazole-4-carboxylic acid 1-cyclohexyloxycarbonyloxy-ethyl ester::Amias::Atacand::Blopress::CANDESARTAN CILEXETIL::CHEMBL1014::Candesartan::Kenzen::Parapres::TCV-116::candesartancilexetil

SMILES CCOc1nc2cccc(C(=O)OC(C)OC(=O)OC3CCCCC3)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1

InChI Key InChIKey=GHOSNRCGJFBJIB-UHFFFAOYSA-N

Data  2 KI  11 IC50  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50318907   

TargetNEDD8-activating enzyme E1 catalytic subunit(Homo sapiens)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50318907(2-Ethoxy-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmet...)
Affinity DataKd:  1.95E+5nMAssay Description:Binding affinity to biotin-labeled GST-tagged NAE (unknown origin) incubated for 1 hr by SPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed