BDBM50506482 CHEMBL4547257::US11311527, Cpd ID I-1::US11376246, Cpd ID I-1::US11576906, Compound I-1

SMILES Cn1c(ccc(NCc2cc3cc(Cl)ccc3[nH]c2=O)c1=O)C#N

InChI Key InChIKey=PDMDNRKCRBOWOM-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50506482   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50506482(CHEMBL4547257 | US11311527, Cpd ID I-1 | US1137624...)
Affinity DataIC50:  40nMAssay Description:Inhibition of recombinant human Myc-DDK-tagged IDH1 R132H mutant using alpha-ketoglutarate as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed