BDBM25617 N-[3-({5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl}carbonyl)-2,4-difluorophenyl]propane-1-sulfonamide::PLX4720
SMILES CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(Cl)cc23)c1F
InChI Key InChIKey=YZDJQTHVDDOVHR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 25617
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human GST-tagged BRAF V600E mutant expressed in baculovirus expression systemMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The Institute of Cancer Research
Curated by ChEMBL
The Institute of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant human full length GST-tagged BRAF expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: 670nMAssay Description:Displacement of 6-amino-9-(2-((4-((2-((6-((5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamido)-2-methylphenyl)carbamoyl)quinolin-2-yl)oxy)ethyl)amino)-...More data for this Ligand-Target Pair