BDBM50380399 CHEMBL2018302::Tubastatin A::US10227295, Compound Tubastatin A::US10456394, Tubastatin A::US11207431, Example D::US8748451, 6::US9249087, Tubacin::US9751832, Tubastatin A::US9956192, Compound Tubastatin-A
SMILES CN1CCc2c(C1)c1ccccc1n2Cc1ccc(cc1)C(=O)NO
InChI Key InChIKey=GOVYBPLHWIEHEJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50380399
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
European Molecular Biology Laboratory
Curated by ChEMBL
European Molecular Biology Laboratory
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of tubastatin-Alexa647-tracer binding to recombinant GST-tagged HDAC10 (unknown origin) measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
European Molecular Biology Laboratory
Curated by ChEMBL
European Molecular Biology Laboratory
Curated by ChEMBL
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of recombinant full-length C-terminal FLAG-fused/His-tagged human HDAC1 expressed in baculovirus infected Sf9 insect cells measured after ...More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
European Molecular Biology Laboratory
Curated by ChEMBL
European Molecular Biology Laboratory
Curated by ChEMBL
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of recombinant full-length C-terminal His-tagged human HDAC2 expressed in baculovirus infected Sf9 insect cells measured after 40 mins by ...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
European Molecular Biology Laboratory
Curated by ChEMBL
European Molecular Biology Laboratory
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of dye-labeled tracer binding to HDAC6 (unknown origin) transfected in human HeLa cells measured after 2 hrs by nano-luciferase reporter g...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
European Molecular Biology Laboratory
Curated by ChEMBL
European Molecular Biology Laboratory
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in baculovirus infected insect cells measured after 40 mins by HDAC...More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
European Molecular Biology Laboratory
Curated by ChEMBL
European Molecular Biology Laboratory
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of dye-labeled tracer binding to HDAC10 (unknown origin) transfected in human HeLa cells measured after 2 hrs by nano-luciferase reporter ...More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
European Molecular Biology Laboratory
Curated by ChEMBL
European Molecular Biology Laboratory
Curated by ChEMBL
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) express...More data for this Ligand-Target Pair