BDBM14390 5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phenyl]-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one::5-{2-ethoxy-5-[(4-methylpiperazine-1-)sulfonyl]phenyl}-1-methyl-3-propyl-1H,6H,7H-pyrazolo[4,3-d]pyrimidin-7-one::CHEMBL192::SILDENAFIL CITRATE::Sildenafil::Sildenafil#::US11155558, Compound sildenafil::US11242347, Compound sildenafil::US11897890, Compound sildenafil::Viagra
SMILES CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(C)CC1
InChI Key InChIKey=BNRNXUUZRGQAQC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 14390
Affinity DataIC50: 6.60nMAssay Description:Inhibition of Phosphodiesterase 5More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Bayer
Curated by ChEMBL
Bayer
Curated by ChEMBL
Affinity DataIC50: >500nMAssay Description:Inhibition of Phosphodiesterase 4More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Bayer
Curated by ChEMBL
Bayer
Curated by ChEMBL
Affinity DataIC50: >500nMAssay Description:Inhibition of Phosphodiesterase 3More data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B(Bos taurus)
Bayer
Curated by ChEMBL
Bayer
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of Phosphodiesterase 1More data for this Ligand-Target Pair