BDBM11694 (2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidine-2-carbonitrile::BMCL15687 Compound 3::CHEMBL307636::Cyclohexylglycine-(2S)-cyanopyrolidine 3::Cyclohexylglycine-(2S)-cyanopyrrolidine 2

SMILES N[C@@H](C1CCCCC1)C(=O)N1CCC[C@H]1C#N

InChI Key InChIKey=SXNUNNAPZNTPQV-RYUDHWBXSA-N

Data  3 KI  18 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 11694   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM11694((2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidin...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity towards Dipeptidyl peptidase IV (DPP-IV)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Rattus norvegicus (rat))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM11694((2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidin...)
Affinity DataIC50:  2.80nMAssay Description:Inhibitory activity against Dipeptidyl peptidase IV (DPP-IV) obtained from rat plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM11694((2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidin...)
Affinity DataIC50:  1.02E+5nMAssay Description:In vitro inhibitory activity against Dipeptidyl peptidase II (DPP II) obtained form bovine kidney homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM11694((2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidin...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM11694((2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidin...)
Affinity DataIC50:  4.10E+4nMAssay Description:In vitro inhibitory activity against Post-proline cleaving enzyme (PPCE) obtained from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM11694((2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidin...)
Affinity DataIC50:  3.15nMAssay Description:Inhibitory activity against Dipeptidyl peptidase IV (DPP-IV) obtained from human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed