BDBM50346552 CHEMBL1797936

SMILES Cc1cc(-c2ccc(C=c3c(=C)[nH]n(-c4ccc(cc4)C(O)=O)c3=O)o2)c(cc1C)[N+]([O-])=O

InChI Key InChIKey=QZBUMRNGAHPCMI-UHFFFAOYSA-N

Data  3 KI  18 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50346552   

TargetHistone acetyltransferase p300(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50346552(CHEMBL1797936)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of EP300 (unknown origin) by AlphaLISA immunodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50346552(CHEMBL1797936)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CBP (unknown origin) using biotinylated H4 (1 to 25)-GSGSK peptide as substrate incubated for 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone acetyltransferase KAT5(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50346552(CHEMBL1797936)
Affinity DataIC50:  3.72E+4nMAssay Description:Inhibition of GST tagged human TIP60 expressed in Sf9 cells using biotinylated H4 (1 to 25)-GSGSK peptide as substrate incubated for 1 hr by AlphaLIS...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone acetyltransferase KAT7(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50346552(CHEMBL1797936)
Affinity DataIC50:  7.81E+3nMAssay Description:Inhibition of MYST2 (unknown origin) using biotinylated H4 (1 to 25)-GSGSK peptide as substrate incubated for 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6B(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50346552(CHEMBL1797936)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of MYST4 (unknown origin) using biotinylated H4 (1 to 25)-GSGSK peptide as substrate incubated for 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone acetyltransferase KAT2B(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50346552(CHEMBL1797936)
Affinity DataIC50:  3.89E+4nMAssay Description:Inhibition of GST tagged human PCAF (431 to end residues) expressed in Sf9 cells using biotinylated H3 (1 to 21)-GGK peptide as substrate incubated f...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone acetyltransferase KAT2A(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50346552(CHEMBL1797936)
Affinity DataIC50:  4.74E+4nMAssay Description:Inhibition of GST tagged human GCN5 (323 to end residues) expressed in Sf9 cells using biotinylated H3 (1 to 21)-GGK peptide as substrate incubated f...More data for this Ligand-Target Pair
In DepthDetails PubMed