BDBM439497 US10633379, Example 35::US10633379, Example 82

SMILES CCNC(=O)c1cc2c(cn(C)c(=O)c2[nH]1)-c1cc(ccc1Oc1c(C)cc(F)cc1C)C(C)(C)O

InChI Key InChIKey=OEDSFMUSNZDJFD-UHFFFAOYSA-N

Data  14 KI  12 IC50  4 Kd

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 439497   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Cnrs

Curated by ChEMBL
LigandPNGBDBM439497(US10633379, Example 35 | US10633379, Example 82)
Affinity DataKd:  520nMAssay Description:Inhibition of BRD4-BD1 (unknown origin) assessed as dissociation constant by TR-FRET methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Cnrs

Curated by ChEMBL
LigandPNGBDBM439497(US10633379, Example 35 | US10633379, Example 82)
Affinity DataKd:  1.60nMAssay Description:Inhibition of BRD4-BD2 (unknown origin) assessed as dissociation constant by TR-FRET methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed