BDBM11682 2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethylamino)ethyl]phenyl N-ethyl-N-methylcarbamate::Rivastigmine.tartrate::US9586925, Rivastigmine

SMILES CCN(C)C(=O)Oc1cccc(c1)[C@H](C)N(C)C

InChI Key InChIKey=XSVMFMHYUFZWBK-NSHDSACASA-N

Data  2 KI  112 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 11682   

TargetCholinesterase(Homo sapiens (Human))
Julius Maximilian University Of W�Rzburg

Curated by ChEMBL
LigandPNGBDBM11682(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)
Affinity DataIC50:  301nMAssay Description:Pseudo-irreversible inhibition of human BChE using butyrylthiocholineiodide as substrate preincubated for 20 to 60 mins followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetAcetylcholinesterase(Homo sapiens (Human))
Julius Maximilian University Of W�Rzburg

Curated by ChEMBL
LigandPNGBDBM11682(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)
Affinity DataIC50:  1.50E+3nMAssay Description:Pseudo-irreversible inhibition of human AChE using acetylthiocholineiodide as substrate preincubated for 20 to 60 mins followed by substrate addition...More data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank