BDBM50010483 CHEMBL2181202

SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O

InChI Key InChIKey=FIAKHZXVLBNZLW-NFGXINMFSA-N

Data  12 KI  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50010483   

TargetMu-type opioid receptor(CALF)
TBA

Curated by ChEMBL
LigandPNGBDBM50010483(CHEMBL2181202)
Affinity DataKi:  0.140nMAssay Description:Displacement of [3H]DAMGO from calf thalamus membrane MOP by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50010483(CHEMBL2181202)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]U69593 from mouse brain membrane KOP by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50010483(CHEMBL2181202)
Affinity DataKi:  2.41E+3nMAssay Description:Binding affinity to KOP (unknown origin) by two-site binding modelMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMu-type opioid receptor(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50010483(CHEMBL2181202)
Affinity DataIC50:  1.40nMAssay Description:Antagonist activity at guinea pig ileum MOPMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMu-type opioid receptor(MOUSE)
TBA

Curated by ChEMBL
LigandPNGBDBM50010483(CHEMBL2181202)
Affinity DataIC50:  23nMAssay Description:Antagonist activity at mouse vas deferns MOPMore data for this Ligand-Target Pair
In DepthDetails PubMed