BDBM102619 K02288a::US10688093, Compound 382_0087_0284::US11701353, Compound 382_0087_0284

SMILES COc1cc(cc(OC)c1OC)-c1cc(cnc1N)-c1cccc(O)c1

InChI Key InChIKey=CJLMANFTWLNAKC-UHFFFAOYSA-N

Data  16 IC50

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 102619   

LigandPNGBDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
Affinity DataIC50:  34nMAssay Description:Inhibition of GST-tagged human recombinant ALK3 expressed in insect cells using casein as substrate in presence of [gamma-32P]ATP incubated for 45 mi...More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of GST-tagged human recombinant ALK1 expressed in baculovirus expression system using casein as substrate in presence of [gamma-32P]ATP in...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetActivin receptor type-1(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of GST-tagged human recombinant ALK2 (145 to 509 residues) expressed in baculovirus expression system using casein as substrate in presenc...More data for this Ligand-Target Pair