BDBM50380399 CHEMBL2018302::Tubastatin A::US10227295, Compound Tubastatin A::US10456394, Tubastatin A::US11207431, Example D::US8748451, 6::US9249087, Tubacin::US9751832, Tubastatin A::US9956192, Compound Tubastatin-A

SMILES CN1CCc2c(C1)c1ccccc1n2Cc1ccc(cc1)C(=O)NO

InChI Key InChIKey=GOVYBPLHWIEHEJ-UHFFFAOYSA-N

Data  13 KI  331 IC50  2 EC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50380399   

TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAc as substrateMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)
Affinity DataIC50:  1.64E+4nMAssay Description:Inhibition of human recombinant HDAC1 using RHKKAc as substrateMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant HDAC2 using RHKKAc as substrateMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)
Affinity DataIC50:  850nMAssay Description:Inhibition of human recombinant HDAC8 using RHKAcKAc as substrateMore data for this Ligand-Target Pair
In DepthDetails PubMed