BDBM50603992 CHEMBL5179988
SMILES CC(C)(N)CNc1nn2c(cnc2s1)-c1ccc(F)cc1F
InChI Key InChIKey=ZJKIGHOTHYACFW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50603992
TargetSerine/threonine-protein kinase haspin(Human)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of hERG by Qpatch-clamp methodMore data for this Ligand-Target Pair
Affinity DataKd: 200nMAssay Description:Binding affinity to human CDK7More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataKd: 100nMAssay Description:Binding affinity to human FLT3More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase haspin(Human)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataKd: 10nMAssay Description:Binding affinity to human HASPINMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Human)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataKd: 200nMAssay Description:Binding affinity to human PIM1More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-2(Human)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataKd: 200nMAssay Description:Binding affinity to human PIM2More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-3(Human)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataKd: 100nMAssay Description:Binding affinity to human PIM3More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Human)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataKd: 1.50E+3nMAssay Description:Binding affinity to human KITMore data for this Ligand-Target Pair