BDBM21278 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide::Acomplia::CHEMBL111::CHEMBL558598::RIMONABANT HYDROCHLORIDE::Rimonabant::SR 141716A::SR141716::SR141716A::[3H]Rimonabant::[3H]SR141716A
SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
InChI Key InChIKey=JZCPYUJPEARBJL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 21278
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 92.5nMAssay Description:Binding affinity to human CB2 receptor expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.76E+3nMAssay Description:Displacement of [3H]WIN552122 from human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.53nMAssay Description:Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 1.76E+3nMAssay Description:Displacement of [3H]WIN55,212-2 from human recombinant CB2 receptor expressed in CHO-K1 cell membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 108nMAssay Description:Inverse agonist activity at human recombinant CB1 receptor expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Inhibition of CYP2C9 in human liver microsomes after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: >20nMAssay Description:Inhibition of CYP2D6 in human liver microsomes after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: >20nMAssay Description:Inhibition of CYP3A4 in human liver microsomes after 30 minsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Green Cross
Curated by ChEMBL
Green Cross
Curated by ChEMBL
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human ERG at holding potential of -80 mV to +40 mVMore data for this Ligand-Target Pair
Affinity DataIC50: >20nMAssay Description:Inhibition of CYP1A2 in human liver microsomes after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.53nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in Sprague-Dawley rat cerebellum after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.76E+3nMAssay Description:Displacement of [3H]WIN-55212-2 from human CB2 receptor expressed in CHO-K1 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair