BDBM50334158 1'-benzyl-3-(2-fluoroethyl)-3H-spiro[[2]benzofuran-1,4'-piperidine::CHEMBL1645202::CHEMBL2314421

SMILES FCCC1OC2(CCN(Cc3ccccc3)CC2)c2ccccc12

InChI Key InChIKey=LDFPQKADFLEDQV-UHFFFAOYSA-N

Data  12 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50334158   

TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50334158(1'-benzyl-3-(2-fluoroethyl)-3H-spiro[[2]benzofuran...)
Affinity DataKi:  0.590nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50334158(1'-benzyl-3-(2-fluoroethyl)-3H-spiro[[2]benzofuran...)
Affinity DataKi:  372nMAssay Description:Displacement of radioligand from kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50334158(1'-benzyl-3-(2-fluoroethyl)-3H-spiro[[2]benzofuran...)
Affinity DataKi:  456nMAssay Description:Displacement of radioligand from mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed