BDBM19190 (1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one::CHEMBL131::Delta-Cortef::Deltacortril::Prednisolone::US10196374, Prednisolone
SMILES [H][C@@]12CC[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
InChI Key InChIKey=OIGNJSKKLXVSLS-VWUMJDOOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 19190
Affinity DataKi: 5.30nMAssay Description:Displacement of radiolabeled dexamethasone from GRMore data for this Ligand-Target Pair
Affinity DataEC50: 26nMAssay Description:Agonist activity at GR expressed in rat H4IIEC3 cells assessed as induction of PEPCK transactivation by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Transrepression activity at GR expressed in NHDF cells assessed as IL-1beta-mediated IL-6 transcription by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 5.30nMAssay Description:Agonist activity at GR expressed in african green monkey CV1 cells transfected with luciferase gene linked to MMTV promoter assessed as induction of ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Transrepression activity at GR expressed in IL-1beta- and TNFalpha-stimulated HepG2 cells assessed as inhibition of NFKB- or AP-1 mediated E-selectin...More data for this Ligand-Target Pair