BDBM50344421 2-((2-chlorophenyl)ethynyl)-6-methyl-7,8-dihydro-1,6-naphthyridin-5(6H)-one::CHEMBL1779851
SMILES CN1CCc2nc(ccc2C1=O)C#Cc1ccccc1Cl
InChI Key InChIKey=MKOHNZFXFNTIQA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50344421
Affinity DataKi: 7.90E+3nMAssay Description:Displacement of [3H]-MPEP from human mGluR5 expressed in HEK293 cells after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 916nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as inhibition of L-glutamate-induced calcium mobilization by FLIPR ...More data for this Ligand-Target Pair