BDBM82551 C18130::CAS_105618-26-6::NOR-BNI (HCI)2::NORBNI
SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2[C@@H]4Oc6c7c(C[C@H]8N(CC9CC9)CC[C@@]47[C@@]8(O)Cc2c1C[C@@]35O)ccc6O
InChI Key InChIKey=APSUXPSYBJVPPS-YAUKWVCOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 29 hits for monomerid = 82551
Affinity DataKi: 0.0700nMAssay Description:Displacement of [3H]diprenorphine from opioid receptor kappa 1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:Effect on binding affinity of mutational exchange of Glu297 in the Opioid receptor kappa 1 in transiently expressed rat cos-7 cells activity expresse...More data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Binding affinity using [3H]diprenorphine as the radioligand against wild-type Opioid receptor kappa 1 in COS-7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Displacement of [3H]diprenorphine from delta-W284E-receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 0.260nMAssay Description:Binding affinity of compound was measured against Opioid receptor kappa 1 on electrically stimulated guinea pig ileal longitudinal muscle myenteric p...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 0.280nMAssay Description:The binding affinity on kappa-opioid receptor using [3H]- U-69,593 as radioligandMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 0.280nMAssay Description:Binding affinity for k opioid receptor was determined using [3H]U-69593 radioligand in Guinea pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.390nMAssay Description:Displacement of [3H]- diprenorphine from mu-W318A-receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.390nMAssay Description:Displacement of [3H]- diprenorphine from mu-W318A-receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.770nMAssay Description:Mutant factor against mu-[K303E] with Opioid receptor kappa 1 for binding affinityMore data for this Ligand-Target Pair
Affinity DataKi: 0.940nMAssay Description:Binding affinity using [3H]diprenorphine as the radioligand against K303E Opioid receptor mu 1 in COS-7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.39nMAssay Description:Displacement of [3H]diprenorphine from k-Y312A-receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:Displacement of [3H]- diprenorphine from delta-receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 12.8nMAssay Description:Binding affinity using [3H]diprenorphine as the radioligand against E297A mutant Opioid receptor kappa 1 in COS-7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 12.9nMAssay Description:Binding affinity using [3H]diprenorphine as the radioligand against E297K mutant Opioid receptor kappa 1 in COS-7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Mutant factor of the compound against kappa[E297K] with Opioid receptor kappa 1 for binding affinity.More data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:Binding affinity against Opioid receptor delta 1 was measured in the guinea pig brain membranes using [3H]DADLE in the presence of 1 uM unlabeled DAM...More data for this Ligand-Target Pair
Affinity DataKi: 41.5nMAssay Description:Displacement of [3H]- diprenorphine from mu-K303E-receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Binding affinity for delta opioid receptor was determined using radioligand [3H]DPDPE in Guinea pig brain membranes.More data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:The binding affinity on delta-opioid receptor using [3H]- DPDPE as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 47nMAssay Description:Binding affinity of compound was measured against Opioid receptor mu 1 on electrically stimulated guinea pig ileal longitudinal muscle myenteric plex...More data for this Ligand-Target Pair
Affinity DataKi: 47nMAssay Description:The binding affinity against mu-opioid receptor using [3H]- DAMGO as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 47nMAssay Description:Binding affinity for mu opioid receptor was determined using radioligand [3H][D-Ala2,MePhe4,Gly-ol6]enkephalin (DAMGO) in Guinea pig brain membranes.More data for this Ligand-Target Pair
Affinity DataKi: 56.6nMAssay Description:Displacement of [3H]- diprenorphine from mu-receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Binding affinity using [3H]diprenorphine as the radioligand against wild-type Opioid receptor mu 1 in COS-7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 102nMAssay Description:Effect on binding affinity of mutational exchange of Lys303 in the Opioid receptor mu 1 in transiently expressed rat cos-7 cells activity expressed a...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against delta-opioid receptor in mouse vas deferens preparation using DADLEMore data for this Ligand-Target Pair
Affinity DataIC50: 8.30nMAssay Description:Inhibitory activity against mu-opioid receptor in guinea pig ileum longitudinal muscle using morphineMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataIC50: 181nMAssay Description:Inhibitory activity against kappa-opioid receptor in guinea pig ileum longitudinal muscle using ethylketazocineMore data for this Ligand-Target Pair