BDBM50027536 (phosphonoformate)Trisodium phosphonoformate::Antiviral agent : Inhibitor of reverse transcriptase of Human T-cell lymphotropic, virus type III, useful in the treatment of HSV-1 infections::CHEMBL754::EHB-776::FOSCARNET SODIUM::Foscarnet::Foscavir::phosphonoformate trisodium salt::trisodium dioxidophosphinecarboxylate oxide::trisodium dioxidophosphinecarboxylate oxide with 6 molecules of water(foscarnet)::trisodium phosphonoformate

SMILES [O-]C(=O)P([O-])([O-])=O

InChI Key InChIKey=ZJAOAACCNHFJAH-UHFFFAOYSA-K

Data  14 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50027536   

TargetCarbonic anhydrase 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50027536((phosphonoformate)Trisodium phosphonoformate | Ant...)
Affinity DataKi:  5.60E+5nMAssay Description:Inhibition of human recombinant CA7 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50027536((phosphonoformate)Trisodium phosphonoformate | Ant...)
Affinity DataKi:  8.20E+5nMAssay Description:Inhibition of human recombinant CA4 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 13(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50027536((phosphonoformate)Trisodium phosphonoformate | Ant...)
Affinity DataKi:  8.70E+5nMAssay Description:Inhibition of mouse recombinant CA13 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50027536((phosphonoformate)Trisodium phosphonoformate | Ant...)
Affinity DataKi:  1.29E+6nMAssay Description:Inhibition of human recombinant CA12 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50027536((phosphonoformate)Trisodium phosphonoformate | Ant...)
Affinity DataKi:  1.81E+6nMAssay Description:Inhibition of human recombinant CA6 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50027536((phosphonoformate)Trisodium phosphonoformate | Ant...)
Affinity DataKi:  2.21E+6nMAssay Description:Inhibition of human recombinant CA9 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50027536((phosphonoformate)Trisodium phosphonoformate | Ant...)
Affinity DataKi:  3.60E+6nMAssay Description:Inhibition of human recombinant CA14 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50027536((phosphonoformate)Trisodium phosphonoformate | Ant...)
Affinity DataKi:  1.18E+7nMAssay Description:Inhibition of human recombinant CA5B by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50027536((phosphonoformate)Trisodium phosphonoformate | Ant...)
Affinity DataKi:  1.42E+7nMAssay Description:Inhibition of human recombinant CA2 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50027536((phosphonoformate)Trisodium phosphonoformate | Ant...)
Affinity DataKi:  2.41E+7nMAssay Description:Inhibition of cloned human CA1 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50027536((phosphonoformate)Trisodium phosphonoformate | Ant...)
Affinity DataKi:  4.17E+7nMAssay Description:Inhibition of human recombinant CA5A by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed