BDBM50325537 CHEMBL1224310::CHEMBL1229095::S-(2-Chlorobenzyl)isothiourea hydrochloride::cid_199161

SMILES NC(=N)SCc1ccccc1Cl

InChI Key InChIKey=SFKYKNIIEFCNBX-UHFFFAOYSA-N

Data  5 IC50  4 EC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50325537   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50325537(CHEMBL1224310 | CHEMBL1229095 | S-(2-Chlorobenzyl)...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of indoleamine-2,3-dioxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
University Of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50325537(CHEMBL1224310 | CHEMBL1229095 | S-(2-Chlorobenzyl)...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of indoleamine-2,3-dioxygenase in human A431 cells assessed as inhibition of IFN-gamma-stimulated kynurenine productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed