BindingDB BDBM10872 4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-sulfonamide::CHEMBL7146::aromatic/heteroaromatic sulfonamide 17

BDBM10872 4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-sulfonamide::CHEMBL7146::aromatic/heteroaromatic sulfonamide 17

SMILES Nc1ccc(cc1)S(=O)(=O)NCCc1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=WODATDPNMUWSHD-UHFFFAOYSA-N

Data 96 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10872

Carbonic anhydrase 2(Homo sapiens (Human))
Union Life Sciences

Curated by ChEMBL

BDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)

Ki: 50nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Filter my 96 hits

Targets 18▿
- Carbonic anhydrase 2 32
- Carbonic anhydrase 1 27
- Carbonic anhydrase 12
- Carbonic anhydrase 9 6
- Carbonic anhydrase 6 3
- Carbonic anhydrase 12 2
- Carbonic anhydrase 13 2
- Beta-carbonic anhydrase 1 2
- Carbonic anhydrase 15 [19-324] 1
- CARBONIC ANHYDRASE 1
- Carbonic anhydrase 14 1
- Carbonic anhydrase, alpha family 1
- Carbonic anhydrase 7 1
- Delta carbonic anhydrase 1
- Carbonic anhydrase 5A, mitochondrial 1
- Carbonic anhydrase 3 1
- Carbonic anhydrase 5B, mitochondrial 1
- Carbonic anhydrase 4 1
- ...
Publications 39▿
- Bioorg Med Chem Lett 21: 710-4 (2011) 5
- Bioorg Med Chem Lett 13: 1005-9 (2003) 4
- Bioorg Med Chem Lett 26: 4184-90 (2016) 4
- Bioorg Med Chem Lett 26: 401-5 (2016) 4
- Bioorg Med Chem Lett 15: 971-6 (2005) 4
- Bioorg Med Chem Lett 14: 3757-62 (2004) 4
- J Med Chem 50: 381-8 (2007) 4
- Bioorg Med Chem 23: 2303-9 (2015) 3
- Bioorg Med Chem 17: 1158-63 (2009) 3
- J Med Chem 49: 2117-26 (2006) 3
- Bioorg Med Chem Lett 16: 2182-8 (2006) 3
- Bioorg Med Chem Lett 15: 963-9 (2005) 3
- Bioorg Med Chem 20: 1403-10 (2012) 3
- Bioorg Med Chem Lett 15: 3828-33 (2005) 3
- J Med Chem 48: 7860-6 (2005) 3
- Bioorg Med Chem 17: 5054-8 (2009) 3
- Bioorg Med Chem Lett 15: 2359-64 (2005) 3
- Bioorg Med Chem Lett 19: 4929-32 (2009) 2
- Bioorg Med Chem Lett 19: 6649-54 (2009) 2
- Bioorg Med Chem 23: 1728-34 (2015) 2
- Bioorg Med Chem 19: 5023-30 (2011) 2
- Bioorg Med Chem 25: 3555-3561 (2017) 2
- J Med Chem 56: 1761-71 (2013) 2
- Bioorg Med Chem 23: 526-31 (2015) 2
- Bioorg Med Chem Lett 26: 1821-6 (2016) 2
- Bioorg Med Chem Lett 26: 1941-6 (2016) 2
- Bioorg Med Chem 17: 4503-9 (2009) 2
- Bioorg Med Chem 24: 1115-20 (2016) 2
- J Med Chem 52: 646-54 (2009) 2
- Bioorg Med Chem 22: 2939-46 (2014) 2
- Bioorg Med Chem 22: 4537-43 (2014) 2
- Bioorg Med Chem 19: 1172-8 (2011) 2
- Bioorg Med Chem 15: 7229-36 (2007) 1
- J Med Chem 55: 3513-20 (2012) 1
- Bioorg Med Chem Lett 24: 275-9 (2013) 1
- Bioorg Med Chem Lett 14: 3283-90 (2004) 1
- J Med Chem 52: 2226-32 (2009) 1
- J Med Chem 52: 3116-20 (2009) 1
- Bioorg Med Chem Lett 26: 1253-9 (2016) 1
Institutions 16▿
- Universit£ 31
- Kochi Medical School 23
- Centre Scientifique De Monaco 8
- University Of Tampere And Tampere University Hospital 5
- Cnr 4
- University Of Tampere 4
- Slovak Academy Of Sciences 3
- Ospedale San Lazzaro 3
- Balikesir University 3
- Recep Tayyip Erdogan University 2
- University Of Montpellier 2
- University of Tampere 2
- Universite Degli Studi Di Firenze 2
- Istituto Di Biochimica Delle Proteine-Cnr 2
- Union Life Sciences 1
- Laxmi Fumigation And Pest Control (P) 1
Affinity: 1.3 to 1.4E+5 nM▿
- Ki 96
- Affinity ≤ nM
Xtal structures: 0
Docked structures: 0
Catalog Cmpds: 0