BDBM19151 (1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-bis(propan-2-yl)-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone::Antibiotic FR 901228::CHEMBL343448::Depsipeptide::FK228::Romidepsin
SMILES C\C=C1/NC(=O)[C@H]2CSSCC\C=C\[C@H](CC(=O)N[C@H](C(C)C)C(=O)N2)OC(=O)[C@@H](NC1=O)C(C)C
InChI Key InChIKey=OHRURASPPZQGQM-GCCNXGTGSA-N
Data 15 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 19151
TargetHistone deacetylase 1(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of HDAC1 by fluorimetric assay in presence of DTTMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Affinity DataIC50: 620nMAssay Description:Inhibition of HDAC6 by fluorimetric assay in presence of DTTMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of HDAC6 by fluorimetric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Affinity DataIC50: 510nMAssay Description:Inhibition of HDAC4 by fluorimetric assayMore data for this Ligand-Target Pair