BDBM50395221 CHEMBL2164663::US9150581, RTI-7527-153

SMILES Fc1ncc(cc1-c1ccc(cc1)C(F)(F)F)C1CC2CCC1N2

InChI Key InChIKey=VKYSIJWKGXVHKX-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50395221   

TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50395221(CHEMBL2164663 | US9150581, RTI-7527-153)
Affinity DataKi: >2.00E+3nMAssay Description:Displacement of [125I]iodoMLA from rat cerebral cortex alpha7 nAChR at 50 nM incubated for 2 hrs by microplate scintillation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50395221(CHEMBL2164663 | US9150581, RTI-7527-153)
Affinity DataIC50:  4.00E+3nMAssay Description:Antagonist activity at rat alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced response after 2 to 6 day...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed