BDBM50005835 (3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide::1-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide::1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide::3-(2-(dimethylamino)ethyl)-N-methyl-1H-indole-5-methanesulfonamide::3-[2-(dimethylamino)ethyl]-N-methylindole-5-methanesulfonamide::CHEMBL128::SUMATRIPTAN::Sumatran::Sumax
SMILES CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1
InChI Key InChIKey=KQKPFRSPSRPDEB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 21 hits for monomerid = 50005835
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Binding affinity by displacement to human cloned 5-hydroxytryptamine 1D receptor in CHO cells by [3H]-5-HT displacement.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Compound was evaluated for the affinity at 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:Compound was evaluated for the affinity at 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 450nMAssay Description:Compound was evaluated for the affinity at 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 16nMAssay Description:Compound was evaluated for the stimulation of [35S]-GTP-gammaS, binding in CHO cells expressing the 5-hydroxytryptamine 1D receptor.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Binding affinity to human cloned 5-hydroxytryptamine 1B receptor in CHO cells by [3H]-5-HT binding displacement.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 16nMAssay Description:Measurement of agonist induced [35S]-GTP-gammaS, binding in CHO cells stably transfected with 5-hydroxytryptamine 1D receptor.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Compound was evaluated for the affinity at 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Compound was evaluated for the affinity at 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 9.30nMAssay Description:Compound was evaluated for the affinity at 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Displacement of [3H]-5-HT from human 5-hydroxytryptamine 1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 7.30nMAssay Description:Compound was evaluated for the affinity at 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]-5-HT from human 5-hydroxytryptamine 1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1E(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 5.50E+3nMAssay Description:Compound was evaluated for the affinity at 5-hydroxytryptamine 1E receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Displacement of [3H]-5-HT binding from the cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Displacement of [3H]-5-HT binding from cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cells.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 14nMAssay Description:Stimulation of [35S]-GTP-gammaS, binding in CHO cells expressing the 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 6.70nMAssay Description:Displacement of [3H]-5-HT binding from human 5-hydroxytryptamine 1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 14nMAssay Description:Stimulation of [35S]-GTP-gammaS, binding in CHO cells expressing the 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 6.70nMAssay Description:Displacement of [3H]-5-HT binding from the cloned human 5-hydroxytryptamine 1D receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Sus scrofa)
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Displacement of radioligand [3H]5-HT binding to 5-hydroxytryptamine 1D receptor in pig caudate membraneMore data for this Ligand-Target Pair