BDBM50117271 1-(2,6-dimethylphenoxy)-2-propanolamine::1-(2,6-dimethylphenoxy)propan-2-amine::2-(2,6-Dimethyl-phenoxy)-1-methyl-ethylamine::2-(2,6-Dimethyl-phenoxy)-1-methyl-ethylamine(mexiletine)::CHEMBL558::MEXILETINE::Mexitil
SMILES CC(N)COc1c(C)cccc1C
InChI Key InChIKey=VLPIATFUUWWMKC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50117271
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human NaV1.1 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of human NaV1.5 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of mouse NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha [1489-1708](Mus musculus)
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of mouse NaV1.1 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human NaV1.7 by IonWorks quattro automated electrophysiology assayMore data for this Ligand-Target Pair