BDBM50154255 CHEMBL3774926::US10106508, Compound II-1
SMILES O=C1COc2cc3ncnc(Nc4cccc(c4)C#C)c3cc2N1CCCN1CCOCC1
InChI Key InChIKey=BWQQOASTOBPYOA-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50154255
Affinity DataIC50: 880nMAssay Description:Inhibition of EGFR-T790M/L858 mutant (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr b...More data for this Ligand-Target Pair
Affinity DataIC50: 139nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair