BDBM50048908 CHEMBL415788

SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(O)=O

InChI Key InChIKey=DQDBCHHEIKQPJD-ODKJCKIQSA-N

Data  17 KI  4 IC50  13 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50048908   

TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50048908(CHEMBL415788)
Affinity DataKi:  0.140nMAssay Description:Displacement of [3H]-{Nomega-[N-(4-propanoylaminobutyl)aminocarbonyl]}Arg-Arg-ProTyr-Ile-Leu-OH Tris(hydrotrifluoroacetate) from NTSR1 in human HT-29...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 2(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50048908(CHEMBL415788)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]NT(8 to 13 residues) from human NTSR2 expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50048908(CHEMBL415788)
Affinity DataIC50:  0.407nMAssay Description:Displacement of [3H]-{Nomega-[N-(4-propanoylaminobutyl)aminocarbonyl]}Arg-Arg-ProTyr-Ile-Leu-OH Tris(hydrotrifluoroacetate) from NTSR1 in human HT-29...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50048908(CHEMBL415788)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at NTSR1 in human HT-29 cells assessed as induction of intracellular Ca2+ mobilization by fura-2 dye-based spectrofluorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50048908(CHEMBL415788)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at NTSR1 in human HT-29 cells assessed as induction of intracellular Ca2+ mobilization by fura-2 dye-based spectrofluorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed